Telight

Telight

Immunology

Dysregulation of immune cell functions can result in many serious and fatal diseases that require re-modulating the immune cells and restoring their normal response. Monitoring of immune cells while interacting with self-cells, pathogens, and cancer promotes our understanding of immune response or its failure mechanisms.

In recent years, immunotherapy gained high potential in cancer treatment as engineered T cells represent a powerful new approach for targeting cancer and autoimmune disorders. However, there are concerns about safety and off-target toxicity, as well as the development of resistance.

Q-Phase opens new horizons for studying spatiotemporal mechanisms and interactions of immune cells under label-free conditions, thus enabling various applications in research.

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Interaction of CAR-T cells and macrophages with cancer cells

Magnification 10x | PC3

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Super-resolution microscopy is crucial for investigating cell-cell interaction and particularly, microbiological immunity (against bacteria and viruses).

Indeed, due to the small size (few nm to µm) of microbes, studying immune responses on cellular and molecular levels remains challenging in conventional optical microscopy, but this drawback could be overcome using the LiveCodim super-resolution module.

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Mitochondrial dynamics in MDCK cells | Marker: Mitotracker-Orange | Mitochondria movements are visualized with 1 image every 5 seconds

Institut Jacques Monod, Imagoseine imaging facility (CNRS UMR7592 and Université de Paris, France)

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Telight Q-Phase

Telight Q-Phase

Quantitative Phase Imaging

Q-Phase is a patented holographic microscope with high detection sensitivity.

Q-Phase is an ideal solution for experts who desire precise automated segmentation of individual cells for subsequent data analysis. Q-Phase quickly transforms cell features and dynamics into numerical data suitable for comparisons, correlations, and more detailed statistics.

Telight LiveCodim

Telight LiveCodim

From conventional to super-resolution microscopy

LiveCodim is the universal 3-in-1 imaging platform for wide-field, confocal and super resolution microscopy. It is designed to interface with any standard fluorescence microscope and is the solution for live cell imaging with high resolution and low phototoxicity.